Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000141)
Formula Reactant Allopurinol Product Allopurinol-1-riboside
Reactant Info Product Info
Metabolic Enzyme Purine nucleoside phosphorylase (PNP) DME Info
Metabolic Type Conjugation - Conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000140 Allopurinol Allopurinol-1-ribotide Unclear Allopurinol [1]
MR000139 Allopurinol Oxipurinol Oxidation - Oxidation Allopurinol [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000138 Allopurinol-1-ribotide Allopurinol-1-riboside Unclear Allopurinol [1]
References
1 On the metabolism of allopurinol. Formation of allopurinol-1-riboside in purine nucleoside phosphorylase deficiency Biochem Pharmacol. 1983 Jul 15;32(14):2167-74. doi: 10.1016/0006-2952(83)90222-8.
2 Clinical pharmacokinetics of allopurinol Clin Pharmacokinet. 1986 Sep-Oct;11(5):343-53. doi: 10.2165/00003088-198611050-00001.

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