Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000144)
Formula
SVG example
Dehydration
Reactant Almotriptan malate metabolite M1 Product EX01-008
Reactant Info Product Info
Metabolic Enzyme Aldehyde dehydrogenase 1 (ALDH1) DME Info
Metabolic Type Other reaction - Dehydration
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000152 Almotriptan malate Almotriptan malate metabolite M1 Oxidation - Oxidative Deamination Almotriptan malate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008996 Almogran 2-{5-[(pyrrolidine-1-sulfonyl)methyl]-1H-indol-3-yl}acetic acid Oxidation - Oxidative deamination Almogran [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000145 EX01-008 Almotriptan malate metabolite M8 Conjugation - Conjugation Almotriptan malate [1]
References
1 Clinical pharmacokinetics of almotriptan, a serotonin 5-HT(1B/1D) receptor agonist for the treatment of migraine. Clin Pharmacokinet. 2005;44(3):237-46.
2 DrugBank(Pharmacology-Metabolism):Almogran

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