Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000226)
Formula
SVG example
Reactant Ampicillin Product Ampicillin piperazine-2,5- dione
Reactant Info Product Info
Metabolic Enzyme Beta-lactamase (blaB) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000224 Ampicillin 5R,6R-penicilloic acid Unclear Ampicillin [1], [2]
MR000225 Ampicillin 5S,6R-penicilloic acid Unclear Ampicillin [1], [2]
MR000223 Ampicillin Ampicillin penicilloic acid Unclear Ampicillin [1], [2]
References
1 Liquid chromatographic determination of ampicillin and its metabolites in human urine by postcolumn alkaline degradation J Pharm Pharmacol. 1987 Jan;39(1):5-8. doi: 10.1111/j.2042-7158.1987.tb07152.x.
2 Identification of metabolites of ampicillin using liquid chromatography/thermospray mass spectrometry and fast atom bombardment tandem mass spectrometry Biomed Environ Mass Spectrom. 1989 Nov;18(11):983-94. doi: 10.1002/bms.1200181106.

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