Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000261)
Formula Reactant Apremilast metabolite M1/2 Product Apremilast metabolite M9
Reactant Info Product Info
Metabolic Type Hydrolysis - Hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000277 Apremilast Apremilast metabolite M1/2 Unclear Apremilast [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000262 Apremilast metabolite M1/2 Apremilast metabolite M18 Hydrolysis - Hydrolysis Apremilast [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000258 O-desmethyl Apremilast Apremilast metabolite M9 Hydrolysis - Hydrolysis Apremilast [1]
References
1 Disposition, metabolism and mass balance of [(14)C]apremilast following oral administration. Xenobiotica. 2011 Dec;41(12):1063-75.

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