Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR000292)
Formula	Esterase Hydrolysis
	Reactant	Aripiprazole lauroxil		Product	Lauric acid
	Reactant	Reactant Info		Product	Product Info
Metabolic Type	Hydrolysis - Esterase Hydrolysis

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR000291	Aripiprazole lauroxil	N-hydroxymethyl-aripiprazole	Hydrolysis - Esterase Hydrolysis	Aripiprazole lauroxil	[1], [2]

References
1	Aripiprazole Lauroxil: Pharmacokinetic Profile of This Long-Acting Injectable Antipsychotic in Persons With Schizophrenia J Clin Psychopharmacol. 2017 Jun;37(3):289-295. doi: 10.1097/JCP.0000000000000691.
2	Biological conversion of?aripiprazole lauroxil - An N-acyloxymethyl aripiprazole prodrug Results Pharma Sci. 2014 May 2;4:19-25. doi: 10.1016/j.rinphs.2014.04.002.

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