Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000308)
Formula Reactant Artenimol Product Alpha-artenimol-beta-glucuronide
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A9 (UGT1A9) DME Info
UDP-glucuronosyltransferase 2B7 (UGT2B7) DME Info
Metabolic Type Conjugation - O-Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000313 Artenimol Artenimol metabolite D1,D2 Unclear Artenimol [1]
MR000312 Artenimol Artenimol metabolite D10 Unclear Artenimol [1]
MR000310 Artenimol Artenimol metabolite D11 Unclear Artenimol [1]
MR000307 Artenimol Artenimol metabolite D12 Unclear Artenimol [1]
MR000311 Artenimol Artenimol metabolite D3,D4 Unclear Artenimol [1]
MR000314 Artenimol Artenimol metabolite D5,D6 Unclear Artenimol [1]
MR000309 Artenimol Artenimol metabolite D7-D9 Unclear Artenimol [1]
References
1 Antimalarial activity and metabolism of dihydroartemisinin-derived dimer Parasitol Res. 2018 Jul;117(7):2243-2254. doi: 10.1007/s00436-018-5911-x.

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