General Information of This Metabolic Reaction (MR) (ID: MR000321)
Formula Reactant N-desmethylasenapine Product 10,11-dihydroxy-N-desmethyl asenapine
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000326 Asenapine maleate N-desmethylasenapine Unclear Asenapine maleate [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000323 N-desmethylasenapine 11-hydroxy-N-formyl-N-desmethylasenapine Unclear Asenapine maleate [1]
MR000322 N-desmethylasenapine Asenapine maleate glucuronide metabolite Conjugation - Glucuronidation Asenapine maleate [1]
MR000325 N-desmethylasenapine Hydroxy-N-formyl-N-desmethylasenapine Unclear Asenapine maleate [1]
MR000324 N-desmethylasenapine N-desmethylasenapine-N-carbamoylglucuronide Unclear Asenapine maleate [1]
References
1 Asenapine review, part I: chemistry, receptor affinity profile, pharmacokinetics and metabolism. Expert Opin Drug Metab Toxicol. 2014 Jun;10(6):893-903.

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