Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000355)
Formula Reactant Betaxolol Product Betaxolol metabolite M5
Reactant Info Product Info
Metabolic Type Oxidation - N-Dealkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000356 Betaxolol Betaxolol metabolite M1 Oxidation - O-Dealkylation Betaxolol [1]
MR000358 Betaxolol Betaxolol metabolite M2 Oxidation - Oxidation Betaxolol [1]
MR000360 Betaxolol Betaxolol metabolite M3 Conjugation - N-Glucuronidation; O-Glucuronidation Betaxolol [1]
MR000361 Betaxolol Betaxolol metabolite M4 Conjugation - N-Glucuronidation; O-Glucuronidation Betaxolol [1]
MR000359 Betaxolol Betaxolol metabolite M6 Conjugation - N-Glucuronidation; O-Glucuronidation Betaxolol [1]
MR000354 Betaxolol Betaxolol metabolite M8 Conjugation - N-Methylation; O-Methylation Betaxolol [1]
MR000357 Betaxolol Betaxolol metabolite M9 Conjugation - O-Acetylation Betaxolol [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000353 Betaxolol metabolite M5 Betaxolol metabolite M7 Conjugation - N-Methylation; O-Methylation Betaxolol [1]
References
1 An in vitro approach to investigate ocular metabolism of a topical, selective 1-adrenergic blocking agent, betaxolol Xenobiotica. 2015 May;45(5):396-405. doi: 10.3109/00498254.2014.987191.

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