General Information of This Metabolic Reaction (MR) (ID: MR000627)
Formula
SVG example
Reactant N-bidesethylchloroquine Product 7-chloro-4-aminoquinoline
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000626 (R)-chloroquine, N-desethyl N-bidesethylchloroquine Oxidation - N-Dealkylation Chloroquine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004050 SSR-97193 4-amino-7 chloroquinoline Unclear SSR-97193 [2]
References
1 Clinical pharmacokinetics and metabolism of chloroquine. Focus on recent advancements Clin Pharmacokinet. 1996 Oct;31(4):257-74. doi: 10.2165/00003088-199631040-00003.
2 In vitro metabolism of ferroquine (SSR97193) in animal and human hepatic models and antimalarial activity of major metabolites on Plasmodium falciparum. Drug Metab Dispos. 2006 Apr;34(4):667-82.

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