Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR000753)
Formula	Sulfation
	Reactant	Deferasirox metabolite M1		Product	Deferasirox metabolite M7
	Reactant	Reactant Info		Product	Product Info
Metabolic Type	Conjugation - Sulfation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR000754	Deferasirox	Deferasirox metabolite M1	Oxidation - Hydroxylation	Deferasirox	[1], [2]

References
1	Pharmacokinetics, metabolism, and disposition of deferasirox in beta-thalassemic patients with transfusion-dependent iron overload who are at pharmacokinetic steady state Drug Metab Dispos. 2010 May;38(5):808-16. doi: 10.1124/dmd.109.030833.
2	Pharmacokinetics, distribution, metabolism, and excretion of deferasirox and its iron complex in rats Drug Metab Dispos. 2008 Dec;36(12):2523-38. doi: 10.1124/dmd.108.022962.

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