Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000797)
Formula Reactant MPV-1709 Product 3-hydroxy N-methyl-dexmedetomidine
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000802 Dexmedetomidine hydrochloride MPV-1709 Conjugation - N-Methylation Dexmedetomidine hydrochloride [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000799 3-hydroxy N-methyl-dexmedetomidine 3-carboxy N-methyl-dexmedetomidine Unclear Dexmedetomidine hydrochloride [2]
MR000798 3-hydroxy N-methyl-dexmedetomidine Dexmedetomidine-N-methyl O-glucuronide Conjugation - Glucuronidation Dexmedetomidine hydrochloride [2]
References
1 Analytical method development for the simultaneous quantitation of dexmedetomidine and three potential metabolites in plasma J Chromatogr A. 1997 Feb 21;762(1-2):281-91. doi: 10.1016/s0021-9673(96)00965-x.
2 LABEL:EXMEDETOMIDINE HYDROCHLORIDE IN 0.9% SODIUM CHLORIDE injection

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