Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000800)
Formula Reactant MPV-1305 Product Hydroxydexmedetomidine-O-glucuronidation
Reactant Info Product Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000803 Dexmedetomidine hydrochloride MPV-1305 Oxidation - Hydroxylation Dexmedetomidine hydrochloride [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000801 MPV-1305 MPV-1036 Unclear Dexmedetomidine hydrochloride [1]
References
1 Analytical method development for the simultaneous quantitation of dexmedetomidine and three potential metabolites in plasma J Chromatogr A. 1997 Feb 21;762(1-2):281-91. doi: 10.1016/s0021-9673(96)00965-x.

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