Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000889)
Formula
SVG example
Reactant Disulfiram Product Carbon disulfide
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000888 Disulfiram Diethylamine Unclear Disulfiram [1]
MR000885 Disulfiram Diethyldithiocarbamate Unclear Disulfiram [2]
MR000886 Disulfiram Diethyldithiocarbamate s-glucuronide Unclear Disulfiram [1]
MR000884 Disulfiram Diethyldlthiocarbamic acid Unclear Disulfiram [2]
MR000887 Disulfiram Disulfiram metabolite inorganic sulfate Unclear Disulfiram [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005907 Thiram CS2 Unclear Thiram [3]
References
1 IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva:World Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work).
2 Pharmacological effects of diethylthiocarbamic acid methyl ester, the active metabolite of disulfiram? Eur J Pharmacol. 1989 Aug 3;166(3):419-25. doi: 10.1016/0014-2999(89)90354-3.
3 Metabolism of a dithiocarbamate fungicide thiram to carbon disulfide in the rat and its hepatotoxic implications

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