Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001019)
Formula
CYP3A7 ...
SVG example
Reactant Felbamate Product p-hydroxyfelbamate
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A7 (CYP3A7) DME Info
Cytochrome P450 2E1 (CYP2E1) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001020 Felbamate 2-hydroxyfelbamate Oxidation - Oxidation Felbamate [1]
MR001018 Felbamate 2-Phenyl-1,3-propanediol monocarbamate Hydrolysis - Esterase Hydrolysis Felbamate [2]
References
1 LABEL:FELBAMATE suspension
2 Felbamate-induced apoptosis of hematopoietic cells is mediated by redox-sensitive and redox-independent pathways Epilepsy Res. 2002 Jan;48(1-2):57-69. doi: 10.1016/s0920-1211(01)00320-5.

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