Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001495)
Formula
SVG example
Reduction
Reactant 3,4-Dihydroxyphenylacetaldehyde (DOPAL) Product 3,4-dihydroxyphenylethanol
Reactant Info Product Info
Metabolic Type Reduction - Reduction
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006626 Dopamine hydrochloride DHPA Unclear Dopamine hydrochloride [1]
MR001486 Dopamine 3,4-Dihydroxyphenylacetaldehyde (DOPAL) Oxidation - Oxidative Deamination Levodopa [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006627 DHPA DOPAC Unclear Dopamine hydrochloride [1]
MR001494 3,4-Dihydroxyphenylacetaldehyde (DOPAL) 3,4-dihydroxyphenylacetic acid Oxidation - Hydroxylation Levodopa [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006366 SC-47945 DOPET Unclear SC-47945 [3]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006367 DOPET MHPE Unclear SC-47945 [3]
References
1 Membrane bound catechol-O-methytransferase is the dominant isoform for dopamine metabolism in PC12 cells and rat brain
2 DrugBank(Pharmacology-Metabolism)Levodopa
3 Neurotoxicity and metabolism of the catecholamine-derived 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylglycolaldehyde: the role of aldehyde dehydrogenase. Pharmacol Rev. 2007 Jun;59(2):125-50.

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