Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001589)
Formula Reactant Lumiracoxib metabolite M5 Product Lumiracoxib metabolite M8
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001586 Lumiracoxib metabolite M11 Lumiracoxib metabolite M5 Oxidation - Hydroxylation Lumiracoxib [1]
MR014167 Lumiracoxib metabolite M9 Lumiracoxib metabolite M5 Oxidation - Hydroxylation Lumiracoxib [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001590 Lumiracoxib metabolite M5 Lumiracoxib metabolite M2 Other reaction - Sulfonation Lumiracoxib [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001595 Lumiracoxib metabolite M15 Lumiracoxib metabolite M8 Oxidation - Hydroxylation Lumiracoxib [1]
MR001593 Lumiracoxib metabolite M8 Lumiracoxib metabolite M10 Conjugation - Glucuronidation Lumiracoxib [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001593 Lumiracoxib metabolite M8 Lumiracoxib metabolite M10 Conjugation - Glucuronidation Lumiracoxib [1]
MR001591 Lumiracoxib metabolite M8 Lumiracoxib metabolite M12 Oxidation - Hydroxylation Lumiracoxib [1]
MR001592 Lumiracoxib metabolite M8 Lumiracoxib metabolite M4/metabolite M6 Unclear Lumiracoxib [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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