Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001600)
Formula
SVG example
Glucuronidation
Reactant Lumiracoxib metabolite M23 Product Lumiracoxib metabolite M22
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A1 (UGT1A1) DME Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001603 Lumiracoxib Lumiracoxib metabolite M23 Oxidation - Hydroxylation Lumiracoxib [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001599 Lumiracoxib metabolite M23 Lumiracoxib metabolite M25 Unclear Lumiracoxib [1]
MR001598 Lumiracoxib metabolite M23 Lumiracoxib metabolite M9 Unclear Lumiracoxib [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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