General Information of This Metabolic Reaction (MR) (ID: MR001773)
Formula
SVG example
N-Oxidation
Reactant Nizatidine Product Nizatidine N2-oxide metabolite
Reactant Info Product Info
Metabolic Type Oxidation - N-Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001772 Nizatidine N2-monodes-methylnizatidine Oxidation - N-Demethylation Nizatidine [1], [2]
MR001774 Nizatidine Nizatidine sulfoxide metabolite Oxidation - Sulfoxidation Nizatidine [3]
References
1 Hemofiltrability of histamine H2-receptor antagonist, nizatidine, and its metabolites in patients with renal failure J Clin Pharmacol. 1993 Apr;33(4):324-9. doi: 10.1002/j.1552-4604.1993.tb04664.x.
2 Determination of nizatidine and two of its main metabolites in human serum using high-performance liquid chromatography J Chromatogr. 1990 Aug 3;529(2):369-76. doi: 10.1016/s0378-4347(00)83843-8.
3 Nizatidine, an H2-blocker. Its metabolism and disposition in man Drug Metab Dispos. 1986 Mar-Apr;14(2):175-82.

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