Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001791)
Formula
SVG example
Reactant 17-desacetylnorgestimate Product Norgestrel
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001793 Norgestimate 17-desacetylnorgestimate Oxidation - Deacetylation Norgestimate [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001792 Norgestrel Norgestrel glucuronide metabolite Conjugation - O-Glucuronidation Norgestimate [3]
References
1 Metabolism of norgestimate by human gastrointestinal mucosa and liver microsomes in vitro J Steroid Biochem Mol Biol. 1991 Apr;38(4):497-503. doi: 10.1016/0960-0760(91)90338-6.
2 Metabolite identification, reaction phenotyping, and retrospective drug-drug interaction predictions of 17-deacetylnorgestimate, the active component of the oral contraceptive norgestimate. Drug Metab Dispos. 2017 Jun;45(6):676-685.
3 DrugBank(Pharmacology-Metabolism)Norgestimate

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