Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001942)
Formula
SVG example
O-Demethylation
Reactant Papaverine Product Papaverine metabolite M3
Reactant Info Product Info
Metabolic Type Oxidation - O-Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001945 Papaverine Papaverine metabolite M1 Oxidation - O-Demethylation Papaverine [1]
MR001941 Papaverine Papaverine metabolite M2 Oxidation - O-Demethylation Papaverine [1]
MR001946 Papaverine Papaverine metabolite M4 Oxidation - N-Oxidation Papaverine [1]
MR001943 Papaverine Papaverine metabolite M5 Conjugation - O-Methylglucosylation Papaverine [1]
MR001944 Papaverine Papaverine metabolite M6 Conjugation - O-Methylglucosylation Papaverine [1]
References
1 Biotransformation of papaverine and in silico docking studies of the metabolites on human phosphodiesterase 10a Phytochemistry. 2021 Mar;183:112598. doi: 10.1016/j.phytochem.2020.112598.

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