Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002082)
Formula
SVG example
Oxygenation
Reactant Ponatinib metabolite M3 Product Ponatinib metabolite M4
Reactant Info Product Info
Metabolic Type Oxidation - Oxygenation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002086 Ponatinib hydrochloride Ponatinib metabolite M3 Oxidation - Oxidtive Deamination Ponatinib hydrochloride [1]
References
1 In vitro metabolites characterization of ponatinib in human liver microsomes using ultra-high performance liquid chromatography combined with Q-Exactive-Orbitrap tandem mass spectrometry Biomed Chromatogr. 2020 Jun;34(6):e4819. doi: 10.1002/bmc.4819.

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