Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002424)
Formula Reactant Trabectedin metabolite M4b Product Trabectedin metabolite M16d
Reactant Info Product Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002428 Trabectedin Trabectedin metabolite M4b Oxidation - Demethylation; Oxidation Trabectedin [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002423 Trabectedin metabolite M4b Trabectedin metabolite M4a Oxidation - Oxidation Trabectedin [1]
References
1 In vitro studies on the metabolism of trabectedin (YONDELIS) in monkey and man, including human CYP reaction phenotyping Biochem Pharmacol. 2009 May 15;77(10):1642-54. doi: 10.1016/j.bcp.2009.02.020.

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