Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002427)
Formula
SVG example
Oxidation
Reactant Trabectedin metabolite M8a Product Trabectedin metabolite M16e
Reactant Info Product Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002430 Trabectedin Trabectedin metabolite M8a Unclear Trabectedin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002431 Trabectedin Trabectedin metabolite M16e Oxidation - Oxidation; Carboxylic Acid Formation Trabectedin [1]
References
1 In vitro studies on the metabolism of trabectedin (YONDELIS) in monkey and man, including human CYP reaction phenotyping Biochem Pharmacol. 2009 May 15;77(10):1642-54. doi: 10.1016/j.bcp.2009.02.020.

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