Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002729)
Formula
SVG example
Reactant 2-(2-hydroxyethyl)-2-methylsuccinimide Product 2-carboxymethyl-2-methylsuccinimide
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002730 Ethosuximide 2-(2-hydroxyethyl)-2-methylsuccinimide Oxidation - Hydroxylation Ethosuximide [1], [2], [3]
References
1 Chiral aspects of the human metabolism of ethosuximide Biopharm Drug Dispos. 2005 Sep;26(6):225-32. doi: 10.1002/bdd.454.
2 Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of ethosuximide by human hepatic microsomal enzymes. Xenobiotica. 2003 Mar;33(3):265-76.
3 The metabolism of ethosuximide Eur J Drug Metab Pharmacokinet. 1993 Oct-Dec;18(4):349-53. doi: 10.1007/BF03190184.

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