Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002939)
Formula
SVG example
Reactant Deferiprone Product Deferiprone metabolite M1
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2A6 (CYP2A6) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002940 Deferiprone Deferiprone 3-o glucuronide metabolite Unclear Deferiprone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002935 Deferiprone metabolite M1 Deferiprone metabolite M4 Unclear Deferiprone [2]
References
1 Deferiprone glucuronidation by human tissues and recombinant UDP glucuronosyltransferase 1A6: an in vitro investigation of genetic and splice variants. Drug Metab Dispos. 2009 Feb;37(2):322-9.
2 Metabolic activation of deferiprone mediated by CYP2A6 Xenobiotica. 2021 Nov;51(11):1282-1291. doi: 10.1080/00498254.2021.1931729.

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