Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003201)
Formula Reactant Delta2-Pyrroline-2-carboxylate Product Pyr2C
Reactant Info Product Info
Metabolic Enzyme Bifunctional trans-3-hydroxy-L-proline dehydratase/2-epimerase (lhpL) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003203 AK-41099 Delta2-Pyrroline-2-carboxylate Unclear AK-41099 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003202 Pyr2C L-proline Unclear AK-41099 [2]
References
1 Characterization of a Novel cis-3-Hydroxy-l-Proline Dehydratase and a trans-3-Hydroxy-l-Proline Dehydratase from Bacteria J Bacteriol. 2017 Jul 25;199(16):e00255-17. doi: 10.1128/JB.00255-17. Print 2017 Aug 15.
2 Structure of Thermococcus litoralis trans-3-hydroxy-l-proline dehydratase in the free and substrate-complexed form. Biochem Biophys Res Commun. 2019 Aug 13;516(1):189-195.

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