Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003353)
Formula
	Reactant	Apalutamide metabolite M4	Product	Apalutamide metabolite M18
	Reactant	Reactant Info	Product	Product Info

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR003364	Apalutamide	Apalutamide metabolite M4	Hydrolysis - Amide Hydrolysis	Apalutamide	[1]
MR003345	N-desmethyl apalutamide	Apalutamide metabolite M4	Unclear	Apalutamide	[1]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR003352	Apalutamide metabolite M4	Apalutamide metabolite M17	Unclear	Apalutamide	[1]

Other MR(s) Related to The Product of This MR

Other MR(s) That Produce The Product of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR003359	Apalutamide metabolite M15	Apalutamide metabolite M18	Unclear	Apalutamide	[1]
MR003354	Apalutamide metabolite M5	Apalutamide metabolite M18	Unclear	Apalutamide	[1]

References
1	Apalutamide Absorption, Metabolism, and Excretion in Healthy Men, and Enzyme Reaction in Human Hepatocytes Drug Metab Dispos. 2019 May;47(5):453-464. doi: 10.1124/dmd.118.084517.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.