Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003633)
Formula Reactant FRC-8653 Product FRC-8653 Metabolite M1
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A (CYP3A) DME Info
Metabolic Type Oxidation - Dehydrogenation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003635 FRC-8653 FRC-8653 Metabolite M2 Oxidation - Demethylation FRC-8653 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003634 FRC-8653 Metabolite M1 FRC-8653 Metabolite M3 Oxidation - Dehydrogenation; demethylation FRC-8653 [1]
References
1 Metabolism and metabolic inhibition of cilnidipine in human liver microsomes. Acta Pharmacol Sin. 2003 Mar;24(3):263-8.

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