Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003705)
Formula Reactant 4'-oxo 4-HPR Product LAU-7b Metabolite L1
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003704 LAU-7b 4'-oxo 4-HPR Unclear LAU-7b [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003706 LAU-7b Metabolite L1 Hydroxy-4-oxo-4-HPR-O-glucuronide Unclear LAU-7b [2]
MR003707 LAU-7b Metabolite L1 Hydroxy-4-oxo-4-HPR-O-sulfate Unclear LAU-7b [2]
References
1 Characterization of the metabolism of fenretinide by human liver microsomes, cytochrome P450 enzymes and UDP-glucuronosyltransferases. Br J Pharmacol. 2011 Feb;162(4):989-99.
2 Fenretinide metabolism in humans and mice: utilizing pharmacological modulation of its metabolic pathway to increase systemic exposure

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