Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003745)
Formula
Se
SVG example
Reactant LS-187709 Product Betamethasone 21-valerate
Reactant Info Product Info
Metabolic Enzyme Skin esterase (Se) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003737 LS-187709 LS-187709 Metabolite Unclear LS-187709 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR014179 Betamethasone valerate Betamethasone 21-valerate Unclear Betamethasone valerate [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003746 Betamethasone 21-valerate Betamethasone Unclear LS-187709 [3]
MR014180 Betamethasone 21-valerate Betamethasone Unclear Betamethasone valerate [2]
References
1 The metabolism of betamethasone J Endocrinol. 1970 Mar;46(3):379-90. doi: 10.1677/joe.0.0460379.
2 Effects of corticosteroids on the growth and metabolism of fibroblasts cultured from human skin Br J Dermatol. 1978 Sep;99(3):253-61. doi: 10.1111/j.1365-2133.1978.tb01994.x.
3 Simultaneous diffusion and metabolism of betamethasone 17-valerate in the living skin equivalent

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