Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003797)
Formula Reactant AG-1549 Metabolite C23 Product AG-1549 Metabolite C25B
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A1 (Cyp3a1) DME Info
Cytochrome P450 3A2 (Cyp3a2) DME Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003796 AG-1549 AG-1549 Metabolite C23 Oxidation - Oxidationn AG-1549 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003807 AG-1549 Metabolite C23 AG-1549 Metabolite C15 Oxidation - Oxidationn AG-1549 [1]
MR003804 AG-1549 Metabolite C23 AG-1549 Metabolite C9 Oxidation - Oxidationn AG-1549 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003798 AG-1549 Metabolite C25B AG-1549 Metabolite C18 Oxidation - Oxidationn AG-1549 [1]
MR003800 AG-1549 Metabolite C25B AG-1549 Metabolite C22 Oxidation - Oxidationn AG-1549 [1]
MR003802 AG-1549 Metabolite C25B AG-1549 Metabolite C24 Unclear AG-1549 [1]
References
1 Evaluation of capravirine as a CYP3A probe substrate: in vitro and in vivo metabolism of capravirine in rats and dogs

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