Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003967)
Formula	N-demethylation
	Reactant	NSC-172130	Product	Northiaden
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Oxidation - N-demethylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR003969	NSC-172130	Dosulepin S-oxide	Oxidation - S-oxidation	NSC-172130	[1], [2]

Other MR(s) Related to The Product of This MR

Other MR(s) That Metabolize The Produtc of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR003968	Northiaden	Northiaden S-oxide	Oxidation - S-oxidation	NSC-172130	[1], [2]

References
1	Metabolism and pharmacokinetics of dothiepin
2	Assessment of the antidepressant activity of dothiepin and its metabolites by preclinical tests

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.