Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004037)
Formula
GDA
SVG example
Reactant Xanthine Product Guanine
Reactant Info Product Info
Metabolic Enzyme Guanine deaminase (GDA) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004031 Xanthine Uric acid Unclear Xanthine [1], [2]
MR004024 Xanthine XMP Unclear Xanthine [2]
MR007509 Xanthine Uric acid Unclear Inosine [3]
MR000079 Xanthine Uric acid Oxidation - Oxidation Adenosine [4], [5]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010385 Guanosine Guanine Unclear - Unclear Guanosine [6]
References
1 Xanthine oxidoreductase activity is correlated with hepatic steatosis
2 Xanthine metabolism in Bacillus subtilis: characterization of the xpt-pbuX operon and evidence for purine- and nitrogen-controlled expression of genes involved in xanthine salvage and catabolism
3 Metabolism of nicotinamide, adenine and inosine in developing microspore-derived canola (Brassica napus) embryos
4 Adenosine Metabolism: Emerging Concepts for Cancer Therapy Cancer Cell. 2019 Dec 9;36(6):582-596. doi: 10.1016/j.ccell.2019.10.007.
5 Purine signaling pathway dysfunction in autism spectrum disorders: Evidence from multiple omics data. Front Mol Neurosci. 2023 Feb 3;16:1089871. doi: 10.3389/fnmol.2023.1089871.
6 Neuroprotective Effects of Guanosine in Ischemic Stroke-Small Steps towards Effective Therapy

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