Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004118)
Formula Reactant Crizotinib metabolite M10 Product Crizotinib metabolite M2
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004117 Crizotinib Crizotinib metabolite M10 Unclear Crizotinib [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004123 Crizotinib metabolite M4 Crizotinib metabolite M2 Unclear Crizotinib [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004120 Crizotinib metabolite M2 Crizotinib metabolite M6 Oxidation - Hydrolyzationn Crizotinib [1]
MR004121 Crizotinib metabolite M2 Crizotinib metabolite M8 Unclear Crizotinib [1]
MR004119 Crizotinib metabolite M2 Crizotinib metabolite M9 Unclear Crizotinib [1]
References
1 Metabolism, excretion and pharmacokinetics of [14C]crizotinib following oral administration to healthy subjects

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