Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004125)
Formula Reactant Crizotinib metabolite M4 Product Crizotinib metabolite M5
Reactant Info Product Info
Metabolic Type Multi-steps Reaction - Hydrolyzationn; Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004122 Crizotinib Crizotinib metabolite M4 Unclear Crizotinib [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004126 Crizotinib metabolite M4 Crizotinib metabolite M1 Unclear Crizotinib [1]
MR004123 Crizotinib metabolite M4 Crizotinib metabolite M2 Unclear Crizotinib [1]
MR004124 Crizotinib metabolite M4 Crizotinib metabolite M3 Unclear Crizotinib [1]
References
1 Metabolism, excretion and pharmacokinetics of [14C]crizotinib following oral administration to healthy subjects

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