Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004174)
Formula
SVG example
Reactant Dihydrolanosterol Product 4,4-dimethyl-5 alpha-cholesta-8,14-dien-3 beta-ol
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 51B1 (cyp51) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004172 Dihydrolanosterol 32-hydroxy-24,25-dihydrolanosterol (lanost-8-ene-3 beta,32-diol) Unclear Dihydrolanosterol [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004173 32-hydroxy-24,25-dihydrolanosterol (lanost-8-ene-3 beta,32-diol) 4,4-dimethyl-5 alpha-cholesta-8,14-dien-3 beta-ol Unclear Dihydrolanosterol [2]
References
1 Purification and characterization of rat sterol 14-demethylase P450 (CYP51) expressed in Escherichia coli
2 Metabolism of 32-hydroxy-24,25-dihydrolanosterol by purified cytochrome P-45014DM from yeast. Evidence for contribution of the cytochrome to whole process of lanosterol 14 alpha-demethylation

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