Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004532)
Formula Reactant ABT-001 Product ABT-001 Metabolite M-
Reactant Info Product Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004533 ABT-001 ABT-001 Metabolite M- Other reaction - Methylhydroxylation ABT-001 [1], [2]
References
1 Identification of cytochromes P450 involved in the human liver microsomal metabolism of the thromboxane A2 inhibitor seratrodast (ABT-001). Drug Metab Dispos. 1997 Jan;25(1):110-5.
2 High-performance liquid chromatographic determination of seratrodast and its metabolites in human serum and urine

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