Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004605)
Formula Reactant EXR-202 Product Hydroxy-ambroxol
Reactant Info Product Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004608 EXR-202 DBAA Unclear EXR-202 [1]
MR004607 EXR-202 DHTQ Unclear EXR-202 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004606 Hydroxy-ambroxol Methylene-dioxy-ambroxol Unclear EXR-202 [2]
References
1 Identification of CYP3A4 as the predominant isoform responsible for the metabolism of ambroxol in human liver microsomes. Xenobiotica. 2000 Jan;30(1):71-80.
2 Characterization of bromhexine and ambroxol in equine urine: effect of furosemide on identification and confirmation

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