Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004683)
Formula
SVG example
20-reduction
Reactant Methylprednisolone M4 Metabolite Product Methylprednisolone M5 Metabolite
Reactant Info Product Info
Metabolic Enzyme 20-ketosteroid reductase (20-hydroxysteroid dehydrogenase) (kduD) DME Info
Metabolic Type Reduction - 20-reduction
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004682 Methylprednisolone Methylprednisolone M4 Metabolite Oxidation - 6,7-dehydrogenation Methylprednisolone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004684 Methylprednisolone M5 Metabolite Methylprednisolone M6 Metabolite Reduction - 20-reduction Methylprednisolone [1], [2]
References
1 Urinary profile of methylprednisolone and its metabolites after oral and topical administrations
2 Carbonyl reduction pathways in drug metabolism

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.