Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004833)
Formula
SVG example
Reactant 4-(6-Methoxy-2-naphthyl)- butan-2-ol Product 4-(6-hydroxy-2-naphthyl)- butan-2-ol
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004832 Nabumetone 4-(6-Methoxy-2-naphthyl)- butan-2-ol Reduction - Reduction Nabumetone [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004848 4-(6-Methoxy-2-naphthyl)- butan-2-ol 4-(6-Methoxy-2-naphthyl)- butan-2-ol glucuronide Conjugation - O-glucuronidation Nabumetone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004839 4-(6-Hydroxy-2-naphthyl)- butan-2-one 4-(6-hydroxy-2-naphthyl)- butan-2-ol Reduction - Reduction Nabumetone [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004834 4-(6-hydroxy-2-naphthyl)- butan-2-ol 4-(6-hydroxy-2-naphthyl)- butan-2-ol glucuronide (2-OH conjugated) Conjugation - O-glucuronidation Nabumetone [1]
MR004836 4-(6-hydroxy-2-naphthyl)- butan-2-ol 4-(6-hydroxy-2-naphthyl)- butan-2-ol glucuronide (6-OH conjugated) Conjugation - O-glucuronidation Nabumetone [1]
MR004845 4-(6-hydroxy-2-naphthyl)- butan-2-ol 4-(6-hydroxy-2-naphthyl)- butan-2-ol sulfate Conjugation - Sulfonation Nabumetone [1]
References
1 Clinical pharmacokinetics of nabumetone. The dawn of selective cyclo-oxygenase-2 inhibition?

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