Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004877)
Formula
SVG example
Hydrolyzationn
Reactant Nateglinide metabolite M2/M3 Product Nateglinide metabolite M11/M12
Reactant Info Product Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004876 Nateglinide Nateglinide metabolite M2/M3 Oxidation - Hydrolyzationn Nateglinide [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004879 Nateglinide metabolite M1 Nateglinide metabolite M11/M12 Oxidation - Hydrolyzationn Nateglinide [1]
MR004881 Nateglinide metabolite M7 Nateglinide metabolite M11/M12 Oxidation - Hydrolyzationn Nateglinide [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
2 Pharmacokinetics of nateglinide enantiomers and their metabolites in Goto-Kakizaki rats, a model for type 2 diabetes mellitus

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