Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005087)
Formula	HNMT
	Reactant	Histamine	Product	N-methylhistamine
	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	Histamine N-methyltransferase (HNMT)				DME Info

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR005090	Histamine	Imidazole acetic acid	Unclear	Histamine	[1]
MR005089	Histamine	Imidazole acetic acid riboside	Unclear	Histamine	[1]
MR005091	Histamine	N-methyl imidazole acetic acid	Unclear	Histamine	[1]
MR005092	Histamine	T-methylimidazoleacetic acid	Unclear	Histamine	[2]
MR005378	Histamine	1-methylhistamine	Unclear	L-histidine	[3], [4], [5]

Other MR(s) Related to The Product of This MR

Other MR(s) That Metabolize The Produtc of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR005088	N-methylhistamine	N-methyl imidazole acetic acid	Unclear	Histamine	[1]

References
1	DrugBank(Pharmacology-Metabolism):Histamine
2	Metabolism and distribution of exogenous histamine in cats
3	Biomarkers of PEGylated Liposomal Doxorubicin-Induced Hypersensitivity Reaction in Breast Cancer Patients Based on Metabolomics
4	Measurement and characterization of histamine and methylhistamine in human urine under histamine-rich and histamine-poor diets
5	Histidine in Health and Disease: Metabolism, Physiological Importance, and Use as a Supplement

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