General Information of This Metabolic Reaction (MR) (ID: MR005370)
Formula
SVG example
Oxidationn
Reactant 12,12-Dihydroxydodecanoic Acid Product Dodecanedioic Acid
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 4A10 (Cyp4a1) DME Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005369 12-Hydroxydodecanoic Acid 12,12-Dihydroxydodecanoic Acid Oxidation - Oxidationn Lauric acid [1], [2]
References
1 The omega-hydroxlyation of lauric acid: oxidation of 12-hydroxlauric acid to dodecanedioic acid by a purified recombinant fusion protein containing P450 4A1 and NADPH-P450 reductase
2 Cytochrome P450 4A11 inhibition assays based on characterization of lauric acid metabolites

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