Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005458)
Formula Reactant Capmatinib M26 Product Capmatinib M37
Reactant Info Product Info
Metabolic Type Reduction - Hydrogenation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005455 Capmatinib Capmatinib M26 Reduction - Hydrogenation Capmatinib [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005456 Capmatinib M26 Capmatinib M27 Reduction - Hydrogenation Capmatinib [1]
MR005460 Capmatinib M26 Capmatinib M33 Reduction - Hydrogenation Capmatinib [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005459 Capmatinib M37 Capmatinib M10 Reduction - Hydrogenation Capmatinib [1]
References
1 Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite

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