Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005974)
Formula
SVG example
Reactant GTPL-463 Product 4-carboxypyrazole
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2E1 (CYP2E1) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005975 GTPL-463 4-hydroxymethylpyrazole Unclear GTPL-463 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001085 Fomepizole 4-carboxypyrazole Unclear Fomepizole [2], [3]
References
1 DrugBank(Pharmacology-Metabolism):GTPL-463 Fomepizole
2 Kinetics and metabolism of fomepizole in healthy humans Clin Toxicol (Phila). 2012 Jun;50(5):375-83. doi: 10.3109/15563650.2012.683197.
3 Treatment of patients with ethylene glycol or methanol poisoning: focus on fomepizole. Open Access Emerg Med. 2010 Aug 24;2:67-75.

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