General Information of This Metabolic Reaction (MR) (ID: MR006021)
Formula
Reactant 7,12-dioxo-LCA Product 7-oxo-DCA
Reactant Info Product Info
Metabolic Enzyme 12alpha-hydroxysteroid dehydrogenase (12-HSDH) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006020 Oxolithocholic acid 7,12-dioxo-LCA Unclear Oxolithocholic acid [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006023 CA 7-oxo-DCA Unclear Oxolithocholic acid [1]
References
1 Metabolism of oxo-bile acids and characterization of recombinant 12alpha-hydroxysteroid dehydrogenases from bile acid 7alpha-dehydroxylating human gut bacteria. Appl Environ Microbiol. 2018 May 1;84(10). pii: e00235-18.

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