Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006226)
Formula
SVG example
Hydrolyzationn
Reactant Urethane Product N-hydroxyurethane
Reactant Info Product Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006225 Urethane Carbon dioxide Unclear Urethane [1]
MR006227 Urethane Vinyl carbamate Unclear Urethane [2]
References
1 Cytochrome P450 2E1 (CYP2E1) is the principal enzyme responsible for urethane metabolism: comparative studies using CYP2E1-null and wild-type mice
2 Detection of 1,N6-ethenodeoxyadenosine and 3,N4-ethenodeoxycytidine by immunoaffinity/32P-postlabelling in liver and lung DNA of mice treated with ethyl carbamate (urethane) or its metabolites

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