Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006374)
Formula
SVG example
Reactant Sialic acid Product ManNAc
Reactant Info Product Info
Metabolic Enzyme N-acetylneuraminate lyase (nanA) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006379 Sialic acid Pyruvate Unclear Sialic acid [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004579 FT-0661285 N-acetyl-d-mannosamine Other reaction - Epimerization FT-0661285 [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006375 ManNAc ManNAc-6-p Unclear Sialic acid [1]
References
1 Crystal structures and kinetics of N-acetylneuraminate lyase from Fusobacterium nucleatum. Acta Crystallogr F Struct Biol Commun. 2018 Nov 1;74(Pt 11):725-732.
2 Production of N-acetyl-d-neuraminic acid by whole cells expressing Bacteroides thetaiotaomicron N-acetyl-d-glucosamine 2-epimerase and Escherichia coli N-acetyl-d-neuraminic acid aldolase. J Agric Food Chem. 2019 Jun 5;67(22):6285-6291.

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