Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006544)
Formula
CYP2C18 ...
SVG example
Reactant Clobazam Metabolite M9 Product Clobazam Metabolite M5
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C18 (CYP2C18) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006541 Clobazam Clobazam Metabolite M9 Unclear Clobazam [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006545 Clobazam Metabolite M9 Clobazam Metabolite M10 Unclear Clobazam [1]
MR006542 Clobazam Metabolite M9 Clobazam Metabolite M3 Unclear Clobazam [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006547 Clobazam Metabolite M7 Clobazam Metabolite M5 Unclear Clobazam [1]
References
1 Kinetics and metabolism of clobazam in animals and man
2 In vitro characterization of clobazam metabolism by recombinant cytochrome P450 enzymes: importance of CYP2C19. Drug Metab Dispos. 2004 Nov;32(11):1279-86.

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