Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006550)
Formula
DCK
SVG example
Phosphorylation
Reactant Clofarabine Product Clofarabind-5'-monophosphate
Reactant Info Product Info
Metabolic Enzyme Deoxycytidine kinase (DCK) DME Info
Metabolic Type Conjugation - Phosphorylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006554 Clofarabine 2-Clofarabine Unclear Clofarabine [1]
MR006555 Clofarabine 6-Ketoclofarabine Unclear Clofarabine [1]
MR006552 Clofarabine Carboxy-Clofarabinwe Oxidation - Oxidationn Clofarabine [1]
MR006553 Clofarabine Clofarabine glucuronides Conjugation - Glucuronidation Clofarabine [1]
MR006556 Clofarabine Clofarabine sulfates Unclear Clofarabine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006551 Clofarabind-5'-monophosphate Clofarabine triphosphate Conjugation - Phosphorylation Clofarabine [2]
References
1 The distribution, metabolism, and elimination of clofarabine in rats
2 LABEL: CLOFARABINE- clofarabine injection

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